• 연구실 : 혜강관 320호
• 연구실 전화 : 3455
• E-mail : dongjoo@ajou.ac.kr
• 연구관심분야 : 천연물 전합성 및 신규 유기합성 반응의 개발
• 홈페이지 : https://sites.google.com/ajou.ac.kr/ldjlab

• 2007.05 PENNSYLVANIA, UNIV. OF 박사
• 2000.02 서울대학교 석사
• 1998.02 서울대학교 학사

2017.03-Present Associate Professor, College of Pharmacy, Ajou University, South Korea
2013.03-2017.02 Assistant Professor, College of Pharmacy, Ajou University, South Korea
2011.03-2013.02 Assistant Professor, College of Pharmacy, Dankook University, South Korea
2007.04-2010.10 Post-Doctoral Fellow, Memorial Sloan-Kettering Cancer Center, NY, USA

1. Development of New Synthetic Transformations and their Application to Total Synthesis of Biologically Active Natural Products
2. Discovery of Novel Therapeutic Agents by a Wide Range of Synthetic Studies of Chemical Probes and Analogues

1. [논문] 유희선, 김형수, 이량하, 이동주, Diastereoselective Construction of trans-2-Alkyl-6-aryl-3,6-dihydro-2H-pyrans via Dehydrogenative Cycloetherification Promoted by DDQ , ORGANIC LETTERS , Vol.23 , No.3 , pp.1135 -1140 (Feb, 2021)
2. [논문] 조민미, 이동주, 곽영신, Rapid Access to the Structural Core of Aflavinines via Stereoselective Tandem intramolecular Diels-Alder Cycloaddition Controlled by the Allylic 1,3-Strain , ORGANIC LETTERS , Vol.21 , No.16 , pp.6529 -6533 (Aug, 2019)
3. [논문] 유희선, 김형수, 이량하, 이동주, Lewis Acid-Promoted Regio- and Diastereoselective Cross-Coupling of Aryl-Substituted 1,2-Diols and Boronic Acids , JOURNAL OF ORGANIC CHEMISTRY , Vol.84 , No.6 , pp.3566 -3578 (Mar, 2019)
4. [논문] 김형수, 이동주, A Concise Formal Total Synthesis of (±)-Centrolobine via DDQ-Mediated Diastereoselective Allylation and Ring-Closing Metathesis , SYNLETT , Vol.26 , No.18 , pp.2583 -2587 (Sep, 2015)
5. [논문] Arun Naini, 이동주, Amos B. Smith, III, Aruna Raja, Florenz Sasse, Ian Harrier, Raimo Franke, Richard E. Taylor, Yazh Muthukumar, Markus Kalesse, The Synthesis and Biological Evaluation of Desepoxyisotedanolide and a Comparison with Desepoxytedanolide , ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , Vol.54 , No.23 , pp.6935 -6939 (Jun, 2015)

1. [논문] 곽수연, 장홍준, 김영훈, 박영직, 한재혁, 김형수, 백승훈, 이동주, Decagram-Scale Synthesis of N-(1,1-dimethyl-2-[4-(-D-glucopyranosyl)oxy-2-methylphenyl]-2-oxoethyl)-3-methylthiophene-2-carboxamide (GPTC), a Fungicide Isofetamid Metabolite , SYNLETT , pp.221 -224 (Jan, 2024)
2. [논문] 안병연, 이량하, 김형수, 이동주, Concise Stereoselective Total Synthesis of (-)-Hedycoropyran A , JOURNAL OF ORGANIC CHEMISTRY , Vol.88 , No.24 , pp.17172 -17180 (Dec, 2023)
3. [논문] 곽수연, 신일진, 박영직, 이동주, 임성주, 김득준, 장홍준, 김형수, Stereoselective total synthesis of (3Z)- and (3E)-elatenynes , RSC Advances , pp.35920 -35925 (Dec, 2023)
4. [논문] 곽수연, 박영직, 이동주, 임성주, 장홍준, 김득준, 김형수, Total Synthesis and Structure Confirmation of (−)-Asimitrin,a C37 Annonaceous Acetogenin with a Hydroxylated Adjacent Bis-Tetrahydrofuran Core , ORGANIC LETTERS , pp.6659 -6664 (Aug, 2023)
5. [논문] 신일진, 곽수연, 박영직, 이동주, 장홍준, 김득준, 김형수, Highly Stereodivergent Construction of a C2‑Symmetric cis,cis- andtrans,trans-2,6-Dioxabicyclo[3.3.0]octane Framework by DoubleIntramolecular Amide Enolate Alkylation: Total Synthesis of(+)-Laurenidificin and (+)-Aplysiallene , ORGANIC LETTERS , pp.0000 -0000 (Nov, 2022)
6. [논문] 김태우, 김현수, 김동준, 이종국, 장재봉, 이동주, 김석호, Synthesis of 7,2'-Dihydroxy-4',5'-Dimethoxyisoflavanone, a Phytoestrogen with Derma Papilla Cell Proliferative Activity , MOLECULES , pp.6660 -6660 (Oct, 2022)
7. [논문] 이동주, 이지훈, 이철행, 임동유, 전지현, 송임숙, 최민구, Development of Jaspine B analysis using LC-MS/MS and its application: Dose-independent pharmacokinetics of Jaspine B in rats , ANALYTICAL SCIENCE & TECHNOLOGY , Vol.34 , No.2 , pp.37 -45 (Apr, 2021)
8. [논문] 장홍준, 곽수연, 이동주, Juan V. Alegre-Requena, Robert S. Paton, 김득준, 김형수, Asymmetric Total Synthesis and Determination of the Absolute Configuration of (+)-Srilankenyne via Sequence-Sensitive Halogenations Guided by Conformational Analysis. , ORGANIC LETTERS , Vol.23 , No.4 , pp.1321 -1326 (Feb, 2021)
9. [논문] 유희선, 김형수, 이량하, 이동주, Diastereoselective Construction of trans-2-Alkyl-6-aryl-3,6-dihydro-2H-pyrans via Dehydrogenative Cycloetherification Promoted by DDQ , ORGANIC LETTERS , Vol.23 , No.3 , pp.1135 -1140 (Feb, 2021)
10. [논문] 유희선, 김형수, 백승훈, 이동주, Direct and Efficient C(sp3)-H Functionalization of N-Acyl/Sulfonyl Tetrahydroisoquinolines (THIQs) With Electron-Rich Nucleophiles via 2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone (DDQ) Oxidation , FRONTIERS IN CHEMISTRY , pp.629 -629 (Jul, 2020)
11. [논문] 조민미, 이동주, 곽영신, Rapid Access to the Structural Core of Aflavinines via Stereoselective Tandem intramolecular Diels-Alder Cycloaddition Controlled by the Allylic 1,3-Strain , ORGANIC LETTERS , Vol.21 , No.16 , pp.6529 -6533 (Aug, 2019)
12. [논문] 정혜경, 김홍표, 이동주, 백승훈, Structure analysis and antioxidant activities of an amylopectin-typepolysaccharide isolated from dried fruits of Terminalia chebula , CARBOHYDRATE POLYMERS , pp.100 -108 (May, 2019)
13. [논문] 유희선, 김형수, 이량하, 이동주, Lewis Acid-Promoted Regio- and Diastereoselective Cross-Coupling of Aryl-Substituted 1,2-Diols and Boronic Acids , JOURNAL OF ORGANIC CHEMISTRY , Vol.84 , No.6 , pp.3566 -3578 (Mar, 2019)
14. [논문] 서민지, 김인영, 이동민, 이동주, 박석순, 이주연, 정성윤, 최민구, 최은경, 최경숙, Gambogic acid triggers vacuolization-associated cell death in cancer cells via disruption of thiol proteostasis , CELL DEATH & DISEASE , Vol.10 , No.3 , pp.187 -203 (Feb, 2019)
15. [논문] 김홍표, 유희선, 김형수, 이동주, 김석호, DDQ-Promoted Mild and Efficient Metal-Free Oxidative α-Cyanation of N-Acyl/Sulfonyl 1,2,3,4-Tetrahydroisoquinolines , MOLECULES , Vol.23 , No.12 , pp.3223 -3235 (Dec, 2018)
16. [논문] 이동민, 박석순, 김환명, 박상준, 손성향, 윤계순, 이동주, 임준희, 엄용우, 정성윤, 최은경, 최경숙, Pyrrolidine dithiocarbamate reverses Bcl-xL-mediated apoptotic resistance to doxorubicin by inducing paraptosis , CARCINOGENESIS , Vol.1 , No.1 , pp.1 -13 (Jan, 2018)
17. [논문] 권미리, 김인영, 서민지, 이동민, 이동주, 최민구, 최경숙, Ohiobolin A kills human glioblastoma cells by inducing endoplasmic reticulum stress via disruption of thiol proteostasis , ONCOTARGET , pp.106740 -106752 (Dec, 2017)
18. [논문] 최민구, 이동주, 강윤주, 권미화, 남소정, 이지훈, 최광식, 최영아, 한유진, 송임숙, Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats , MARINE DRUGS , pp.279 -295 (Sep, 2017)
19. [논문] 이기연, 권혁래, 신일진, 장홍준, 서재홍, 김형수, 이동주, Total Synthesis of (±)-Decytospolides A and B , SYNLETT , Vol.2 , pp.249 -252 (Jan, 2017)
20. [논문] 신일진, 김형수, 이동주, Substrate-Controlled Asymmetric Total Synthesis and Structure Revision of (?)-Bisezakyne A , ORGANIC LETTERS , Vol.18 , No.17 , pp.4420 -4423 (Aug, 2016)
21. [논문] 이동주, SAHA SHARMISTHA, 김인영, 최경숙, Paraptosis in the anti-cancer arsenal of natural products , PHARMACOLOGY & THERAPEUTICS , Vol.162 , pp.120 -133 (Jun, 2016)
22. [논문] 신일진, 장홍준, 이동주, 김득준, 김형수, Stereoselective Substrate-Controlled Asymmetric Syntheses of both 2,5-cis- and 2,5-trans-Tetrahydrofuranoid Oxylipids: Stereodivergent Intramolecular Amide Enolate Alkylation , ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , pp.6497 -6501 (May, 2016)
23. [논문] 김형수, 이동주, A Concise Formal Total Synthesis of (±)-Centrolobine via DDQ-Mediated Diastereoselective Allylation and Ring-Closing Metathesis , SYNLETT , Vol.26 , No.18 , pp.2583 -2587 (Sep, 2015)
24. [논문] 김규동, 이동주, Pramod K. Sahu, Shuhao Qu, 유진하, 최유진, 정낙신, Stereoselective Synthesis of D-5-Homo-4-Selenoribose as a Versatile Intermediate for 4'-Selenonucleosides , ORGANIC LETTERS , Vol.17 , No.18 , pp.4636 -4639 (Sep, 2015)
25. [논문] Arun Naini, 이동주, Amos B. Smith, III, Aruna Raja, Florenz Sasse, Ian Harrier, Raimo Franke, Richard E. Taylor, Yazh Muthukumar, Markus Kalesse, The Synthesis and Biological Evaluation of Desepoxyisotedanolide and a Comparison with Desepoxytedanolide , ANGEWANDTE CHEMIE-INTERNATIONAL EDITION , Vol.54 , No.23 , pp.6935 -6939 (Jun, 2015)
26. [논문] 이동주, 고은재, 신일진, 서승용, 이기연, 김형수, Total Synthesis of Acetylcholinesterase Inhibitor Macakurzin C , SYNLETT , Vol.25 , No.19 , pp.2794 -2796 (Dec, 2014)
27. [논문] 이동주, 신일진, 황윤정, 서승용, 이기연, 김형수, Concise and stereoselective synthesis of (±)-Hagen's gland lactone , RSC ADVANCES , Vol.4 , pp.52637 -52639 (Oct, 2014)
28. [논문] 임동희, 신일진, 김형수, 이동주, Gram-scale synthesis of anti-pancreatic flavonoids (±)-8-[1-(4′-hydroxy-3′-methoxyphenyl)prop-2-en-1-yl]-chrysin and -galangin , TETRAHEDRON , Vol.70 , No.32 , pp.4738 -4744 (Aug, 2014)
29. [논문] 배훈, 백동재, 전홍준, 이동주, 김상희, Stereochemically Reliable Syntheses of Pachastrissamine and Its 2-epi-Congener via Oxazolidinone Precursors from an Established Starting Material N-tert-butoxycarbonyl-Protected Phytosphingosine , SYNTHESIS-STUTTGART , pp.3609 -3612 (Dec, 2012)
30. [논문] 이동주, A Concise Total Synthesis of 2-epi-(-)-Pachastrissamine via a Three-Component Tandem Cross-Metathesis-Intramolecular SN2' Substitution-Cross-Metathesis Sequence , SYNLETT , pp.2840 -2844 (Dec, 2012)

1. [논문] 이지훈, 이동주, 권미화, 최광익, 최민구, 송임숙, Differential Cytotoxic Effects of Jaspine B in Various Cancer Cells , 생명과학회지 , Vol.26 , No.12 , pp.1392 -1399 (Dec, 2016)

1. [학술회의] 이찬양, 백승훈, 김영훈, 김형수, 문정주, 이동주, Development and uncertainty estimation of acynonapyr certified reference material using mass balance method , 2022 대한약학회 추계국제학술대회 (Oct, 2022)
2. [학술회의] 이찬양, 백승훈, 김영훈, 김형수, 문정주, 이동주, Development and uncertainty estimation of bifenazate certified reference material using mass balance method , 2022 대한약학회 추계국제학술대회 , pp.683 (Oct, 2022)
3. [학술회의] 이찬양, 백승훈, 김영훈, 김형수, 문정주, 이동주, Development and uncertainty estimation of flometoquin certified reference material using mass balance method , 2022 대한약학회 추계국제학술대회 , pp.684 (Oct, 2022)
4. [학술회의] 김민영, 백승훈, 유희선, 이동주, 고현정, 송재형, Structure analysis of pectic polysaccharides isolated from the root of Sanguisorba officinalis , 2022 대한약학회 추계국제학술대회 , pp.835 (Oct, 2022)
5. [학술회의] 이동주, Asymmetric Stereoselective Total Synthesis of trans-2-Aryl-6-alkyl-tetrahydro-2H-pyran Natural Products , 2022 대한약학회 춘계 국제학술대회 심포지엄 (Apr, 2022)
6. [학술회의] 유희선, 이동주, 이종국, 이량하, 황정중, Synthetic Studies of 1,3,5-Dihydrotriazine , 2019 Fall International Convention of Pharmaceutical Society of Korea (Oct, 2019)
7. [학술회의] 유희선, 이동주, A-DDQ-Promoted Diastereoselective Synthesis of Arylated trans-2,6-Disubstituted-3,4-Dihydropyrans , The 12th International Conference on Cutting-Edge Organic Chemistry in Asia/The 3rd Advanced Research Network on Cutting-Edge Organic Chemistry in Asia (Nov, 2017)
8. [학술회의] 이동주, Studies Directed Towards the Total Synthesis of Tetrahydropyranyl Diarylheptanoid Natural Products , The Spring International Convention of the Pharmaceutical Society of Korea (Apr, 2014)

1. [학술회의] 유희선, 이동주, Unified and Divergent Stereoselective Total Syntheses of Isocarbostyril Alkaloids Utilizing Boronic Ester-Mediated Alkenylation Promoted by a Lewis Acid , 제19회 대한약학회 약품화학분과학회 워크샵 (Jun, 2024)
2. [학술회의] 권민정, 김형수, 백승훈, 이동주, Scalable Syntheses of Metabolites SYN545910 & M56 of Herbicides Bicyclopyrone & Tiafenacil , 제19회 대한약학회 약품화학분과학회 워크샵 (Jun, 2024)
3. [학술회의] 손유희, 원영돈, 이동주, 배문형, 서승용, Total Syntheses of Bioactive 2,6-Epoxudiarylheptanoids & Structural Revision of (-)-Tsaokopyranol LL , 제19회 대한약학회 약품화학분과학회 워크샵 (Jun, 2024)
4. [학술회의] 이희연, 김형수, 백승훈, 이동주, 이경진, Development of certified reference material of pyrethrins using mass balance method , 제72회 한국분석과학회 춘계 학술대회 (May, 2024)
5. [학술회의] 이경진, 김형수, 백승훈, 이동주, 이희연, Development of a certified reference materials of SYN545910 using mass balance method , 제72회 한국분석과학회 춘계 학술대회 (May, 2024)
6. [학술회의] 이경진, 김형수, 백승훈, 이동주, 김용준, 김희서, 이희연, Establishment of a certified reference materials of spiropidion and its metabolite spiropidion-enol using mass balance method , 제71회 한국분석과학회 추계 학술대회 (Nov, 2023)
7. [학술회의] 이경진, 김형수, 백승훈, 이동주, 김주엽, 이희연, 하태곤, Development of certified reference material of 5-hydroxy imidacloprid using organic synthesis and mass balance method , 제71회 한국분석과학회 추계 학술대회 (Nov, 2023)
8. [학술회의] 이찬양, 백승훈, 김영훈, 김형수, 이경진, 이동주, Feasibility study on the thermogravimetric analysis as an alternative to volatile and inorganic impurity assays in mass balance method for certified reference standard , 제10회 대한약학회 약품분석학분과 동계심포지엄 및 정기총회 (Jan, 2023)
9. [학술회의] 김영훈, 백승훈, 김형수, 이동주, 이찬양, 이경진, Development of certified reference materials of Imidacloprid using mass balance method and differential scanning calorimetry , 제69회 한국분석과학회 추계 학술대회 , pp.9 (Nov, 2022)
10. [학술회의] 김영훈, 백승훈, 김형수, 이동주, 이찬양, 이경진, Development of certified reference materials of cyclaniliprole using mass balance method and differential scanning calorimetry , 제69회 한국분석과학회 추계 학술대회 , pp.9 (Nov, 2022)
11. [학술회의] 김영훈, 백승훈, 김형수, 이동주, 이찬양, 이경진, Development of certified reference materials of Tiafenacil using mass balance method and differential scanning calorimetry , 제69회 한국분석과학회 추계 학술대회 , pp.9 (Nov, 2022)
12. [학술회의] 김영훈, 백승훈, 김형수, 이동주, 이찬양, 이경진, Development of certified reference materials of Isofetamid and GPTC using mass balance method and differential scanning calorimetry , 제69회 한국분석과학회 추계 학술대회 , pp.9 (Nov, 2022)
13. [학술회의] 이동주, Diastereoselective Construction of Arylated Stereogenic Centers and its Application to Total Synthesis of Natural Products , 제25회 한국유기합성학회 학술대회(워크샵) (Feb, 2022)
14. [학술회의] 김영훈, 김형수, 백승훈, 이동주, 문정주, 박의정, 손유희, 유희선, 이찬양, 장홍준, 한재혁, Development and certification of bifenazate diazene reference material using mass balance method , 제67회 한국분석과학회 추계 학술대회 (Nov, 2021)
15. [학술회의] 유희선, 이동주, 김형수, 백승훈, A General Strategy for the Synthesis of 9-Norneolignans: Enantioselective Total Synthesis of (-)-Agatharesinol, (-)-Agatharesinol Acetonide, (-)-Sugiresinol and ent-(+)-Hinokiresinol , 제17회 대한약학회 약품화학분과학회 워크샵 , pp.53 -53 (Jun, 2021)
16. [학술회의] 유희선, 이동주, 1,3-Asymmetric Induction of Chiral 3-Substituted Tetrahydroisoquinolines Promoted by DDQ , 제15회 대한약학회 약품화학분과학회 워크샵 (Jun, 2019)
17. [학술회의] 이동주, Asymmetric Stereoselective Total Syntheses of (+)-6-epi-Goniothalesdiol A and (+)-Parvistone E, and a Formal Total Synthesis of (-)-8-epi-9-Deoxygoniopypyrone Acetate , 제8회 약품화학워크샵 (Frontiers in Medicinal Chemistry 8th Workshop) (Apr, 2019)
18. [학술회의] 이량하, 이동주, Stereoselective Total Synthesis of (±)-6-epi-Goniothalesdiol A & (±)-Leiocarpin A , 제14회 대한약학회 약품화학분과학회 워크샵 (Jun, 2018)
19. [학술회의] 유희선, 이동주, Diastereoselective Cross-Coupling of Aryl-Substituted Diol and Boronic Acids Promoted by Lewis Acids , 제14회 대한약학회 약품화학분과학회 워크샵 (Jun, 2018)
20. [학술회의] 이동주, Lewis Acid-Promoted Regio- and Diastereoselective Cross-Coupling of Aryl-Substituted Diols with Boronic Acids , 제7회 약품화학워크샵 (Frontiers in Medicinal Chemistry 7th Workshop) (Mar, 2018)
21. [학술회의] 이동주, Oxidative Functionalization at the Benzylic Postion and its Application to Natural Product Synthesis , 2017 한국유기합성학회 WORK SHOP (Mar, 2017)
22. [학술회의] 이동주, A diastereoselective Synthesis of Arylated Dihydropyrns Utilizing DDQ-Promoted Oxidative Intramolecular Etherification , 제6회 약품화학워크샵 (Frontiers in Medicinal Chemistry 6th Workshop (Mar, 2017)

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