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김소희
김소희
  • 박사
  • 약학전공(과)
 교직원
정보
  • 연구실 : 약학관308호
  • 연구실 전화 : 3451
  • E-mail : shkim67@ajou.ac.kr
  • 연구관심분야 : 약물학/약동학
  • 홈페이지 :
학력
  • 1998.02 서울대학교대학원 박사
  • 1991.02 서울대학교대학원 석사
  • 1989.02 서울대학교 학사
경력 
1991 ? 1994		서울대학교병원 약제부 약사
1998 ? 2001	    강원대학교 대학원 약학과 시간강사
1998 ? 2001		서울대학교 약학대학 박사후 연구원
2001 ? 2012		강릉대학교 치과대학 약리학전공 조교수/부교수/교수
2004 ?/2006		웨인주립대학교 의과대학 Visiting Assistant Professor
2010 ? 2012 		미시간주립대학교 의과대학 암연구소 Research Fellow
2012 ? Present	아주대학교 약학대학 약학과 교수
논문 및 연구활동 연구활동(주요논문)
  1. [논문] 이재명, 방은숙, 이주원, 정태석, 김소희, Single-Center Pharmacokinetic Study and Simulation of a Low Meropenem Concentration in Brain-Dead Organ Donors , ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , Vol.62 , No.10 , pp.1 -12 (Oct, 2018)
  2. [논문] Nada E, Ramnath N, Beer DG, Christensen PJ, Colacino J, Esteller M, Jeon CK, Rozek LS, Sandoval J, 김소희, Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma , JOURNAL OF THORACIC ONCOLOGY , Vol.9 , No.4 , pp.473 -482 (Apr, 2014)
  3. [논문] 김소희, Amanda N. King, Bruce Hollis, Chae Kyung Jeon, Dafydd G. Thomas, David G. Beer, Dean E. Brenner, Guoan Chen, Lili Zhao, Paul J. Christensen, Robert U. Simpson, Thomas J. Giordano, Nithya Ramnath, Characterization of vitamin D receptor (VDR) in lung adenocarcinoma , LUNG CANCER , Vol.77 , No.2 , pp.265 -271 (Aug, 2012)
  4. [논문] 김소희, Chen G, Beer DG, Beer DG, Christensen PJ, Giordano TJ, King AN, Lili Zhao, Lin L, Simpson RU , Thomas DG, Wang Z, Ramnath N, CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma , CLINICAL CANCER RESEARCH , Vol.17 , No.4 , pp.817 -826 (Mar, 2011)
  5. [논문] 김소희, Miller FR, Tait L, Zheng J, Novak RF, Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograph lesions: Biomarkers of progression , INTERNATIONAL JOURNAL OF CANCER , Vol.124 , No.12 , pp.2813 -2828 (Jun, 2009)
국제학술논문지
  1. [논문] 김수연, 지혜진, 김소희, 박주영, 배성훈, 김은하, 정이숙, 이승호, Hypnotic effect of AR-001 through adenosine A1 receptor , European Journal of Pharmacology , pp.176847 -176847 (Oct, 2024)
  2. [논문] 반지혜, 김민경, 김준현, 박신영, 서봉교, 유윤미, 이동기, 채정용, 김소희, Nonclinical Pharmacokinetics Study of OLX702A-075-16, N-Acetylgalactosamine Conjugated Asymmetric Small Interfering RNA (GalNAc-asiRNA) , DRUG METABOLISM AND DISPOSITION , pp.1262 -1270 (Aug, 2024)
  3. [논문] 최현겸, 박소연, 배성훈, 장선영, 김소희, Loganin Ameliorates Acute Kidney Injury and Restores Tofacitinib Metabolism in Rats: Implications for Renal Protection and Drug Interaction , Biomolecules & Therapeutics , pp.601 -610 (Aug, 2024)
  4. [논문] 최현겸, 김은아, 박소연, 배성훈, Bao Loc Nguyen, 김종오, 오수진, 이수빈, 김소희, 임수정, Pre-mixing of omega-3 fatty acid-containing liposomes enhances the drug release rate and therapeutic efficacy of anticancer drugs loaded in liposomes , JOURNAL OF CONTROLLED RELEASE , pp.410 -424 (Feb, 2024)
  5. [논문] 원종문, 최현겸, 김장희, 박소연, 김소희, Effects of Hyperlipidemia on the Pharmacokineticsof Tofacitinib, a JAK 1/3 Inhibitor, in Rats , Pharmaceutics , Vol.15 , pp.2195 -2195 (Aug, 2023)
  6. [논문] 배성훈, 김형수, 박소연, 장선영, 최현겸, 김소희, Effects of Isosakuranetin on Pharmacokinetic Changes of Tofacitinib in Rats with N-Dimethylnitrosamine-Induced Liver Cirrhosis , Pharmaceutics , pp.2684 -2684 (Dec, 2022)
  7. [논문] 박선영, 정예서, 박소연, 김소희, Role of AMPK in Regulation of Oxaliplatin-Resistant HumanColorectal Cancer , Biomedicines , pp.2690 -2690 (Oct, 2022)
  8. [논문] 배성훈, 김효성, 장선영, 최현겸, 김소희, Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats , Biomolecules & Therapeutics , pp.510 -519 (Jul, 2022)
  9. [논문] 박소연, 유희영, 장선영, 김소희, Regulation of Butyrate-Induced Resistance through AMPK Signaling Pathway in Human Colon Cancer Cells , BIOMEDICINES , Vol.9 , No.11 , pp.1604 -1617 (Nov, 2021)
  10. [논문] 박휘진, 배성훈, 김소희, Dose-independent pharmacokinetics of loganin in rats: effect of intestinal first-pass metabolism in bioavailability , JOURNAL OF PHARMACEUTICAL INVESTIGATION , Vol.51 , pp.767 -776 (Sep, 2021)
  11. [논문] 이지상, 김효성, 정용섭, 최현겸, 김소희, Pharmacokinetic Drug Interaction between Tofacitinib and Voriconazole in Rats , PHARMACEUTICS , pp.740 -740 (May, 2021)
  12. [논문] 배성훈, 장선영, 김소희, Slower Elimination of Tofacitinib in Acute Renal Failure Rat Models: Contribution of Hepatic Metabolism and Renal Excretion , PHARMACEUTICS , pp.12 -714 (Jul, 2020)
  13. [논문] 곽은혜, 유희영, 김소희, Effects of Diabetes Mellitus on the Disposition of Tofacitinib, a Janus Kinase Inhibitor, in Rats , BIOMOLECULES & THERAPEUTICS , Vol.4 , pp.361 -369 (Jul, 2020)
  14. [논문] 김지은, 박문영, 김소희, Simple determination and quantification of tofacitinib, a JAK inhibitor, in rat plasma, urine and tissue homogenates by HPLC and its application to a pharmacokinetic study , JOURNAL OF PHARMACEUTICAL INVESTIGATION , pp.603 -612 (May, 2020)
  15. [논문] 이지상, 김소희, Dose-Dependent Pharmacokinetics of Tofacitinib in Rats: Influence of Hepatic and Intestinal First-Pass Metabolism , PHARMACEUTICS , pp.318 -318 (Jul, 2019)
  16. [논문] 김미선, 김소희, 김영인, 이은제, 정이숙, Takao Iwawaki, 고현정, 김성열, 장선영, ERdj5 in innate immune cells is a crucial factor for the mucosal adjuvanticity of cholera toxin , FRONTIERS IN IMMUNOLOGY , Vol.10 , pp.1 -11 (Jun, 2019)
  17. [논문] 이재명, 방은숙, 이주원, 정태석, 김소희, Single-Center Pharmacokinetic Study and Simulation of a Low Meropenem Concentration in Brain-Dead Organ Donors , ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , Vol.62 , No.10 , pp.1 -12 (Oct, 2018)
  18. [논문] 배성훈, 박주호, Choi Hyeon Gyeom, Kim Hyesook, 김소희, Imidazole Antifungal Drugs Inhibit the Cell Proliferation and Invasion of Human Breast Cancer Cells , BIOMOLECULES & THERAPEUTICS , Vol.26 , No.5 , pp.494 -502 (Sep, 2018)
  19. [논문] 최용준, 김소희, 이지상, Jin Y, 옥소영, 정윤석, Urinary Pentosidine levels negatively associates with trabecular bone scores in patients with type 2 diabetes mellitus , OSTEOPOROSIS INTERNATIONAL , Vol.29 , No.4 , pp.907 -915 (Apr, 2018)
  20. [논문] 이지상, 장선영, 정윤석, 정이숙, 김소희, Simple Quantification of Pentosidine in Human Urine and Plasma by High-Performance Liquid Chromatography , INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY , Vol.2017 , pp.1389807 -1389807 (Oct, 2017)
  21. [논문] 홍순석, 김소희, 김종오, 이미경, 최주연, 임수정, Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation , INTERNATIONAL JOURNAL OF NANOMEDICINE , Vol.11 , pp.4465 -4477 (Sep, 2016)
  22. [논문] 강향리, 임수정, 전채경, 최현겸, 김소희, Butyrate-mediated acquisition of chemoresistance by human colon cancer cells , ONCOLOGY REPORTS , Vol.36 , No.2 , pp.1119 -1126 (Aug, 2016)
  23. [논문] 두은신, 문홍식, 임수정, 김소희, Pharmacokinetics of YJC-10592, a novel chemokine receptor 2 (CCR-2) antagonist, in rats , ARCHIVES OF PHARMACAL RESEARCH , Vol.39 , No.6 , pp.833 -842 (Jun, 2016)
  24. [논문] 두은신, 장선영, 문홍식, 임수정, 김소희, High performance liquid chromatographic determination of YJC-10592, a new chemokine receptor 2 (CCR-2) antagonist,in biological samples , JOURNAL OF PHARMACEUTICAL INVESTIGATION(약제학회지) , Vol.46 , No.5 , pp.495 -504 (May, 2016)
  25. [논문] Soo-Jeong Lim, Chae Kyung Jeon, Hyeon Gyeom Choi, 김소희, Increased chemoresistance to paclitaxel in the MCF10AT series of human breast epithelial cancer cells , ONCOLOGY REPORTS , Vol.33 , No.4 , pp.2023 -2030 (Apr, 2015)
  26. [논문] Soon-Seok Hong, 김소희, Soo-Jeong Lim, Effects of triglycerides on the hydrophobic drug loading capacity of saturated phosphatidylcholine-based liposomes , INTERNATIONAL JOURNAL OF PHARMACEUTICS , Vol.483 , No.1-2 , pp.142 -150 (Feb, 2015)
  27. [논문] 이은혜, 김소희, 이미경, 홍순석, 임수정, 임준석, Computed tomography-guided screening of surfactant effect on blood circulation time of emulsions: application to the design of an emulsion formulation for paclitaxel , PHARMACEUTICAL RESEARCH , Vol.31 , No.8 , pp.2022 -2034 (Aug, 2014)
  28. [논문] Nada E, Ramnath N, Beer DG, Christensen PJ, Colacino J, Esteller M, Jeon CK, Rozek LS, Sandoval J, 김소희, Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma , JOURNAL OF THORACIC ONCOLOGY , Vol.9 , No.4 , pp.473 -482 (Apr, 2014)
  29. [논문] 정윤석, 최용준, 김소희, Improved dosage form of the combined alendronate and calcitriol (maxmarvil®) on the absorption of alendronate in korean postmenopausal women , ARCHIVES OF PHARMACAL RESEARCH , Vol.36 , pp.966 -972 (Aug, 2013)
  30. [논문] Si Hyung Yang, Hyeon Gyeom Choi, Myung Gull Lee, Soo-Jeong Lim, 김소희, Effects of morin on the pharmacokinetics of etoposide in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in female Sprague-Dawley rats , ONCOLOGY REPORTS , Vol.29 , No.3 , pp.1215 -1223 (Mar, 2013)
  31. [논문] Si Hyung Yang, Jung Hwa Suh, Myung Gull Lee, 김소희, Pharmacokinetic Drug Interactions between Ondansetron and Tamoxifen in Female Sprague-Dawley Rats with DMBA-induced Mammary Tumor , ANTICANCER RESEARCH , Vol.33 , pp.521 -528 (Feb, 2013)
  32. [논문] 김소희, Amanda N. King, Bruce Hollis, Chae Kyung Jeon, Dafydd G. Thomas, David G. Beer, Dean E. Brenner, Guoan Chen, Lili Zhao, Paul J. Christensen, Robert U. Simpson, Thomas J. Giordano, Nithya Ramnath, Characterization of vitamin D receptor (VDR) in lung adenocarcinoma , LUNG CANCER , Vol.77 , No.2 , pp.265 -271 (Aug, 2012)
  33. [논문] 임수정, 고성희, 김수연, 박완서, 이은명, 이은혜, 차준형, 최현겸, 최환호, 김소희, Docosahexaenoic acid sensitizes colon cancer cells to sulindac sulfide-induced apoptosis , ONCOLOGY REPORTS , Vol.27 , pp.2023 -2030 (Mar, 2012)
  34. [논문] Sukyoung Kim, 김소희, Eun-Hye Lee, Sunho Lee, Soo-Jeong Lim, Comparison of Three Tocopherol Analogs as an Inhibitor of Production of Proinflammatory Mediators in Macrophages , JOURNAL OF PHARMACOLOGICAL SCIENCES , Vol.118 , pp.237 -244 (Feb, 2012)
  35. [논문] 서정화, 김소희, Lee HJ, Yoon IS, 강희은, 심창구, 양시형, 이명걸, Cysteine effects on the pharmacokinetics of etoposide in rats with protein-calorie malnutrition rats: Increased gastrointestinal absorption by cysteine , XENOBIOTICA , Vol.41 , No.10 , pp.885 -894 (Oct, 2011)
  36. [논문] 양시형, 육군주, 이대영, 이명걸, 이주현, 김소희, Effects of morin on the pharmacokinetics of docetaxel in rats with 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumors , ARCHIVES OF PHARMACAL RESEARCH , Vol.34 , No.10 , pp.1729 -1734 (Oct, 2011)
  37. [논문] 김소희, Christensen PJ, Ramnath N, Vitamin D and lung cancer , Expert Review of Respiratory Medicine , Vol.5 , No.3 , pp.305 -309 (May, 2011)
  38. [논문] 김소희, Chen G, Beer DG, Beer DG, Christensen PJ, Giordano TJ, King AN, Lili Zhao, Lin L, Simpson RU , Thomas DG, Wang Z, Ramnath N, CYP24A1 is an independent prognostic marker of survival in patients with lung adenocarcinoma , CLINICAL CANCER RESEARCH , Vol.17 , No.4 , pp.817 -826 (Mar, 2011)
  39. [논문] 안충렬, 김소희, 강희은, 배수경, 배수현, 이멸걸, 신완균, Pharmacokinetics of sildenafil and its metabolite, N-desmethylsildenafil, in rats with liver cirrhosis and diabetes mellitus, alone and in combination , XENOBIOTICA , Vol.41 , No.2 , pp.164 -174 (Feb, 2011)
  40. [논문] 김민정, 김소희, 임수정, Comparison of the apoptosis-inducing capability of sulforaphane analogs in human colon cancer cells , ANTICANCER RESEARCH , Vol.30 , No.9 , pp.3611 -3620 (Sep, 2010)
  41. [논문] 이은지, 김소희, 촤영희, 이병구, Pharmacokinetics of itraconazole in diabetic rats , ANTIMICROBIAL AGENTS AND CHEMOTHERAPY , Vol.54 , No.2 , pp.931 -933 (Feb, 2010)
  42. [논문] 조유경, 김소희, 최영희, 이명걸, Effects of E. coli lipopolysaccharide on the metformin pharmacokinetics in rats , XENOBIOTICA , Vol.39 , No.12 , pp.946 -954 (Dec, 2009)
  43. [논문] 이대영, 김소희, 이은지, 이인철, 졍혜진, 최영희, 이명걸, Pharmacokinetics of ipriflavone and its two metabolites, M1 and M5, after the intravenous and oral administration of ipriflavone to rat model of diabetes mellitus induced by streptozotocin , EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES , Vol.38 , No.5 , pp.465 -471 (Dec, 2009)
  44. [논문] 강희은, 김소희, Baek SR, Sohn SI, 정혜영, 조유경, 이명걸, Pharmacokinetics of liguiritigenin in mice, rats, rabbits and dogs, and animal scale-up , JOURNAL OF PHARMACEUTICAL SCIENCES , Vol.98 , No.11 , pp.4327 -4342 (Nov, 2009)
  45. [논문] 정혜영, 김소희, 강희은, 최영희, 이명걸, Time-dependent effects of Klebsiellapneumoniae endotoxin on the pharmacokinetics of chlorzoxazone and its main metabolite, 6-hydroxychlorzoxazone, in rats: restoration of the parameters in 96 hour in KPLPS rats to control levels , BIOPHARMACEUTICS & DRUG DISPOSITION , Vol.30 , No.8 , pp.485 -493 (Nov, 2009)
  46. [논문] 김소희, Miller FR, Tait L, Zheng J, Novak RF, Proteomic and phosphoproteomic alterations in benign, premalignant and tumor human breast epithelial cells and xenograph lesions: Biomarkers of progression , INTERNATIONAL JOURNAL OF CANCER , Vol.124 , No.12 , pp.2813 -2828 (Jun, 2009)
  47. [논문] 김소희, Zukowski K, Navak RF, Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells , ANTICANCER RESEARCH , Vol.29 , No.4 , pp.1143 -1150 (Apr, 2009)
국내학술논문지
  1. [논문] 이보경, 최리라, 김소희, 장선영, 이두이, 이지인, 정이숙, Staurosporine에 의해 분화된 망막신경절세포에서 산화 스트레스 유도 세포사멸에 대한 차조기 추출물의 보호 효능 , 한국식품영양과학회지 , Vol.46 , No.2 , pp.161 -168 (Feb, 2017)
  2. [논문] 임수정, 김소희, Vitamin D in cancer: effects of pharmaceutical drugs on the vitamin D pharmacokinetics , JOURNAL OF PHARMACEUTICAL INVESTIGATION(약제학회지) , Vol.44 , No.5 , pp.317 -328 (Oct, 2014)
국제학술발표
  1. [학술회의] 최현겸, 김소희, 박소연, 이다연, 장선영, Effect of resveratrol on the pharmacokinetics of tofacitinib in rats with acetaminophen-induced liver injury , 2024 대한약학회 춘계국제학술대회 (Apr, 2024)
  2. [학술회의] 최현겸, 김소희, 이다연, 장선영, 정다운, 정원화, Protective effect of resveratrol on the pharmacokinetics of tofacitinib in rats with cisplatin-induced acute renal failure , 2024 대한약학회 춘계국제학술대회 (Apr, 2024)
  3. [학술회의] 박소연, 김소희, 김현지, 박기현, 장선영, 정원화, Effects of loganin on the pharmacokinetics of voriconazole in ratswith acetaminophen-induced hepatotoxicity , 2024 대한약학회 춘계국제학술대회 (Apr, 2024)
  4. [학술회의] 정용섭, 김소희, 배성훈, 최현겸, Non-competitive inhibition of tofacitinib metabolism by posaconazole in rats , 2021 Fall International Convention of The Pharmaceutical Society of Korea (Dec, 2021)
  5. [학술회의] 배성훈, 김소희, 박소연, 정용섭, Disposition of tofacitinib in ulcerative colitis rat model induced by dextran sulfate sodium , 2021 Fall International Convention of The Pharmaceutical Society of Korea (Dec, 2021)
  6. [학술회의] 배성훈, 김소희, 정예서, 최현겸, Human extrapolation of tofacitinib using PBPK simulation of tofacitinib in renal failure rat model , 2021 Fall International Convention of The Pharmaceutical Society of Korea (Dec, 2021)
  7. [학술회의] 최현겸, 김소희, 김형수, 박소연, 정예서, Anticancer effects of Broussochalcone A through Akt/mTOR signaling pathway in human cancer cells , 2021 Fall International Convention of The Pharmaceutical Society of Korea (Dec, 2021)
  8. [학술회의] 박소연, 김소희, 유희영, 정예서, Regulation of AMPK signaling pathway by butyrate-induced resistant human colon cancer cells , 2021 Fall International Convention of The Pharmaceutical Society of Korea (Dec, 2021)
  9. [학술회의] 정용섭, 김소희, 배성훈, 원종문, 유희영, Increased elimination of tofacitinib, a JAK 1/3 inhibitor, in rats fed a high cholesterol diet , 2021 Spring International Conference of the Pharmaceutical Society of Korea (Apr, 2021)
  10. [학술회의] 최현겸, 김소희, 박소연, 유희영, Mechanism of chemoresistance in the butyrate-induced resistant human colon cancers: Effect of AMPK/ACC signaling pathway , 2021 Spring International Conference of the Pharmaceutical Society of Korea (Apr, 2021)
  11. [학술회의] 정용섭, 김소희, 김효성, 이지상, 최현겸, Non-competitive inhibition of Tofacitinib metabolism by voriconazole in rats , 2021 Spring International Conference of the Pharmaceutical Society of Korea (Apr, 2021)
  12. [학술회의] 최현겸, 김소희, 박선영, 정예서, Mechanism of chemoresistance in the oxaliplatin-resistant human colon cancer: Effects of Akt-mTOR signaling pathway , 2021 Spring International Conference of the Pharmaceutical Society of Korea (Apr, 2021)
  13. [학술회의] 배성훈, 김소희, 박휘진, Dose-independent pharmacokinetics of loganin in rats: Effect of intestinal first-pass metabolism on low bioavailability , 2021 Spring International Conference of the Pharmaceutical Society of Korea (Apr, 2021)
  14. [학술회의] 김효성, 김소희, 배성훈, 이지상, 최현겸, Effects of voriconazole on the metabolism of tofabitinib in rats , 대한약리학회 추계학술대회 (Nov, 2020)
  15. [학술회의] 박예지, 김소희, 김형수, 배성훈, 최현겸, ANTI-CANCER EFFECTS OF ISOSAKURANETIN, AGLYCON OF PONCIRIN, THROUGH AKT-MTOR SIGNALING PATHWAY IN HUMAN CANCERS , 대한약리학회 추계학술대회 (Nov, 2020)
  16. [학술회의] 배성훈, 김소희, 장선영, 정용섭, EFFECTS of ACUTE RENAL FAILURE INDUCED BY GENTAMICIN AND CISPLATIN ON THE ELIMINATION OF TOFACITINIB IN RATS , 대한약리학회 추계학술대회 (Nov, 2020)
  17. [학술회의] 배성훈, 김소희, 장선영, Slower elimination of tofacitinib in acute renal failure rat models: Contribution of hepatic metabolism and renal excretion , 한국응용약물학회 추계국제학술대회 (Oct, 2020)
  18. [학술회의] 김효성, 김소희, 배성훈, 이지상, Pharmacokinetic drug interaction between voriconazole and tofacitinib in rats: noncompetitive inhibition of tofacitinib via CYP3A1/2 and CYP2C11 , 한국응용약물학회 추계국제학술대회 (Oct, 2020)
  19. [학술회의] 박예지, 김소희, 김형수, 배성훈, 최현겸, Isosakuranetin, aglycon of poncirin, inhibit cell proliferation through Akt-mTOR signaling pathway in human cancers , 한국응용약물학회 추계국제학술대회 (Oct, 2020)
  20. [학술회의] 김소희, 약동학적 약물상호작용의 이해와 사례 분석 , 2020 (사)한국응용약물학회 워크샵 (Oct, 2020)
  21. [학술회의] 김소희, 약동학 이해 및 ADME Overview , 2020 (사)한국응용약물학회 워크샵 (Oct, 2020)
  22. [학술회의] 유희영, 김소희, 김효성, 박휘진, BUTYRATE-INDUCED RESISTANCE THROUGH AMPK/ACC SIGNALING PATHWAY IN HUMAN COLON CANCERS , 대한약리학회 추계학술대회 (Nov, 2019)
  23. [학술회의] 원종문, 김소희, 유희영, EFFECTS OF HIGH-CHOLESTEROL DIET ON THE DISPOSITION OF TOFACITINIB, A JAK 1/3 INHIBITOR, IN RATS , 대한약리학회 추계학술대회 (Nov, 2019)
  24. [학술회의] 박휘진, 김소희, 김효성, PHARMACOKINETIC STUDY OF LOGANIN AFTER INTRAVENOUS AND ORAL ADMINISTRATION IN RATS , 대한약리학회 추계학술대회 (Nov, 2019)
  25. [학술회의] 박선영, 김소희, 박예지, 배성훈, 원종문, CHEMORESISTANCE OF OXALIPLATIN THROUGH AKT-MTOR PATHWAY IN COLON CANCERS , 대한약리학회 추계학술대회 (Nov, 2019)
  26. [학술회의] 이재명, 김소희, 배성훈, 정태석, PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING SIMULATION OF TOFACITINIB IN KOREAN POPULATION USING SIMCYP , 대한약리학회 추계학술대회 (Nov, 2019)
  27. [학술회의] 원종문, 김소희, 박선영, 박예지, EFFECTS OF HYPERLIPIDEMIA INDUCED BY POLOXAMER 407 ON THE DISPOSITION OF TOFACITINIB, A JAK 1/3 INHIBITOR, IN RATS , 대한약리학회 추계학술대회 (Nov, 2019)
  28. [학술회의] 유희영, 김소희, Butyrate increases the chemoresistance through AMPK pathway in human colon cancer cell , 한국응용약물학회 추계국제학술대회 (Oct, 2019)
  29. [학술회의] 원종문, 김소희, Hyperlipidemia alters the pharmacokinetics of tofacitinib, a JAK 1/3 inhibitor, in rats , 한국응용약물학회 추계국제학술대회 (Oct, 2019)
  30. [학술회의] 김소희, 약동학 이해 및 주요 파라메터 산출 , 2019(사)한국응용약물학회 워크샵 (Oct, 2019)
  31. [학술회의] 박성욱, 김소희, Effects of grapefruit juice and St.john's wort on the pharmacokinetics of tofacitinib in fats: differentiation of hepatic and intestinal metabolism , 2018 Annual Meeting of the Korean Society of Applied Pharmacology , pp.291 (Oct, 2018)
  32. [학술회의] 김소희, Application of 3D primary hepatocyte culture system to the evaluation of drug metabolism , 3rd Korea-China joint Symposium on Biofabrication and its Applications to Biomedicine (Dec, 2017)
  33. [학술회의] 최용준, 정윤석, 김소희, 이지상, Yilan Jin, 옥소영, Urinary pentosidine levels are negatively associated with trabecular bone score in patients with type 2 diabetes , International Congress of Osteoporosis (ICO) (Nov, 2016)
  34. [학술회의] 홍순석, 김소희, 임수정, 김종오, 이미경, 최주연, Triglyceride incorporation in liposomes enables the production of injectable paclitaxel formulation , International Conference on 70th Anniversary of The Pharmaceutical Society of Korea (Oct, 2016)
  35. [학술회의] 이지상, 김소희, 정윤석, 최용준, Yilan Jin, 옥소영, Trabecular bone score is inversely proportional to urinary pentosidine levels in patients with type 2 diabetes , International Conference on 70th Anniversary of The Pharmaceutical Society of Korea (Oct, 2016)
  36. [학술회의] 이지상, 김소희, 정윤석, Quantification of pentosidine in human urine and plasma by high-performance liquid chromatography , International Conference on 70th Anniversary of The Pharmaceutical Society of Korea (Oct, 2016)
  37. [학술회의] 김지은, 김소희, 박문영, 박주호, 이지상, Development and validation of a high-performance liquid chromatographic method for the quantitation of tofacitinib, a JAK inhibitor, in biological samples and its application to pharmacokinetics , International Conference on 70th Anniversary of The Pharmaceutical Society of Korea (Oct, 2016)
  38. [학술회의] 김소희, Epigenetic Regulation of CYP24A1 in Lung Adenocarcinoma:Alterations in Metabolism of vitamin D , 30th JSSX Annual Meeting (Nov, 2015)
  39. [학술회의] 강향리, 김소희, 김선재, 임수정, The effects of butyrate on chemoresistance in human colon cancer cells , 2015 Proceedings of the Fall International convention of The Pharmaceutical Society of Korea (Oct, 2015)
  40. [학술회의] 배성훈, 김소희, 박유진, 김혜숙, 임수정, 최현겸, Imidazole antifungal drugs inhibited cell proliferation and invasiness in human breast cancer , 2015 추계 대한약학회 학술대회 (Oct, 2015)
  41. [학술회의] Hyesook Kim, 김소희, 배성훈, Aby Joiakim, David Kaplan, David Putt, Detection of increased O-GlcNAcylated p53 levels in MCF-7 cells after O-GlcNAcase inhibitor treatment using antibodies specific for Ser-149-O-GlcNAcylated p53 proteins , AACR (Apr, 2015)
  42. [학술회의] Hyesook Kim, 김소희, Aby Joiakim, David Kaplan, David Putt, Effects of O-GlcNAcase inhibitors on O-GlcNAcylated c-myc expression in MCF-7 cells , An AACR Special Conference on MYC: From Biology to Therapy , pp.48 -48 (Jan, 2015)
  43. [학술회의] 홍순석, 임수정, 김소희, 이미경, Oli-incorporation in saturated phosphatidylchline-based liposomes enhances the loading capacity of a poorly-soluble drug paclitaxel , 2014 AAPS Annual Meeting and Exposition (Nov, 2014)
  44. [학술회의] 손지영, 김소희, 이은혜, 임수정, Increase in chemoresistance of paclitaxel in MCF10AT series of human breast epithelial cancer cells , 2014 Annual Meeting of The Korean Society of Applied Pharmacology, Challenge and Opportunity of Incrementally Modified Drugs by Combination , pp.259 -259 (Oct, 2014)
  45. [학술회의] 두은신, 김소희, 손지영, 임수정, Pharmacokinetics of YJC-10592, a new chemokine receptor-2 (CCR-2) antagonist, in rats , 2014 the Fall International Convention of The Pharmaceutical Society of Korea , pp.211 -211 (Oct, 2014)
  46. [학술회의] 두은신, 김소희, 강향리, 배성훈, Joiakim, Aby, Kaplan, David, Kim, Hyesook, Putt, David, Inhibition of cell Proliferation in cancers by Ketoconazole through O-GlcNAcylation of c-Myc , 2014 Spring International Convention of The Pharceutical Society of Korea , pp.224 -224 (Apr, 2014)
  47. [학술회의] 김소희, 두은신, 박성수, Aby Joiakim, David Kaplan, David Putt, Hyesook Kim, Ketoconazole-induced O-GlcNAcylated c-Myc expression and inhibition of cell proliferation in cancers , 2014 American Association for Cancer Research (AACR) Annual Meeting (Apr, 2014)
  48. [학술회의] 이은혜, 임수정, 김소희, 이미경, 임준석, 홍순석, Application of CT imaging technology for the evaluation of emulsion pharmacokinetics , 2013 Asian Federation for Pharmaceutical Sciences Conference , pp.183 -183 (Nov, 2013)
  49. [학술회의] Min-Jung Kim, Soo-Jeong Lim, 김소희, Soo-Yeon Kim, Young-Mok Kwon, Differential Cytotoxic and Anti-Inflammatory Activities of Sulforaphane Analogues in Murine Macrophages , Proceedings of the Spring International Convention of The Pharmaceutical Society of Korea , pp.178 -178 (Apr, 2013)
  50. [학술회의] Soo-jeong Lim, 김소희, Chae K Jeon, Hyeon G Choi, Chemoresistance is induced by butyrate in colon cancer cells , 2013 AACR Annual Meeting (Apr, 2013)
  51. [학술회의] Hyesook Kim, 김소희, Aby Joiakim, David Kaplan, David Putt, Production of Thr-58-O-GlcNAcylated c-myc antibodies and detection of increased O-GlcNAcylated c-myc levels in MCF-7 cells after ketoconazole treatment , 2013 AACR Annual Meeting , pp.18 -19 (Apr, 2013)
  52. [학술회의] 김소희, Vitamin D and Cyp24A1 in lung adenocarcinoma: Alterations in metabolism of vitamin D , 2012 International Conference of the Korean Society of Pharmaceutical Sciences and technology (Nov, 2012)
  53. [학술회의] 양시형, 김소희, April E Cho, Raymond F Navak, 이은혜, 임수정, Gene expression profiling of MCF10A series of Ha-Ras transformed human breast epithelial cells: Gene expression involved in EMT pathway , 2012 AACR Annual Meeting (Apr, 2012)
  54. [학술회의] 김소희, Chae Kyung Jeon, David G Beer, Guoan Chen, Justin Colacino, Laura S Rozek, Lili Zhao, Nithya Ramnath, Paul J Christensen, Smoking effects on CYP24A1 in lung adenocarcinoma : Epigenetic changes by smoking , 2012 AACR Annual Meeting (Apr, 2012)
국내학술발표
  1. [학술회의] 전하진, 김소희, 견진옥, 방은숙, Vancomycin의 AUC 측정에 사용되는 Bayesian Software Program의비만 환자에 대한 정확도 및 편향도 평가 , 2024년 추계학술대회 (Nov, 2024)
  2. [학술회의] 최현겸, 김소희, 박소연, 장선영, 정원화, Hepatoprotective effect of resveratrol on the pharmacokinetics of tofacitinib in rats with acetaminophen-induced acute liver injury , 2024 제32차 총회 및 추계학술대회 (Oct, 2024)
  3. [학술회의] 최현겸, 김소희, 박기현, 정원화, Effects of loganin on the renal protection and pharmacokinetics of tofacitinibHyeon , 2023 한국응용약물학회 춘계학술대회 (Apr, 2023)
  4. [학술회의] 배성훈, 김소희, 박소연, 정다운, 김유철, PBPK simulation of tofacitinib in human using single species extrapolation ofrenal failure and liver cirrhosis rat model , 2023 한국응용약물학회 춘계학술대회 (Apr, 2023)
  5. [학술회의] 정예서, 김소희, 박소연, 최현겸, Role of AMPK in regulation of oxaliplatin-resistant human colorectal cancer , 2022 대한약학회 추계국제학술대회 (Oct, 2022)
  6. [학술회의] 배성훈, 김소희, 박기현, 정다운, Hepatoprotective effects of isosakuranetin on the metabolism of tofacitinib in liver cirrhosis rats model , 2022 대한약학회 추계국제학술대회 (Oct, 2022)
  7. [학술회의] 배성훈, 김소희, 박기현, 정다운, Effects of Isosakuranetin on Pharmacokinetic Changes of Tofacitinib in Liver Cirrhosis Rats Induced by N-Nitrosodimethylamine , 2022 한국응용약물학회 추계학술대회 (Oct, 2022)
  8. [학술회의] 정예서, 김소희, 박소연, 최현겸, Effects of AMPK in human colorectal cancers resistant to oxaliplatin , 2022 한국응용약물학회 추계학술대회 , pp.412 -412 (Oct, 2022)
  9. [학술회의] 배성훈, 김소희, 박소연, 정용섭, Pharmacokinetics of Tofacitinib in Rats with Ulcerative Colitis Induced by Dextran Sulfate Sodium , 대한약리학회 추계학술대회 (Nov, 2021)
  10. [학술회의] 박소연, 김소희, 유희영, 정예서, Butyrate induced protective autophagy through activation of Akt/mTOR pathway in human colon cancer cells , 대한약리학회 추계학술대회 (Nov, 2021)
  11. [학술회의] 정용섭, 김소희, 배성훈, 최현겸, Pharmacokinetic Drug Interaction Between Tofacitinib and Posaconazole in Rats , 대한약리학회 추계학술대회 (Nov, 2021)
  12. [학술회의] 배성훈, 김소희, 정예서, 최현겸, PBPK Simulation of Tofacitinib in Renal Failure Patients Using Renal Failure Rat Data , 대한약리학회 추계학술대회 (Nov, 2021)
  13. [학술회의] 배성훈, 김소희, 박소연, 정용섭, Effects of ulcerative colitis induced by dextran sulfate sodium on the elimination of tofacitinib in rats , 한국응용약물학회 추계국제학술대회 (Oct, 2021)
  14. [학술회의] 박소연, 김소희, 유희영, 정예서, Regulation of butyrate-induced resistance through AMPK signaling pathway in human colon cancer cells , 한국응용약물학회 추계국제학술대회 (Oct, 2021)
  15. [학술회의] 정용섭, 김소희, 배성훈, 최현겸, Effects of posaconazole on the metabolism of tofacitinib in rats , 한국응용약물학회 추계국제학술대회 (Oct, 2021)
  16. [학술회의] 배성훈, 김소희, 정예서, 최현겸, Physiologically based pharmacokinetic simulation of tofacitinib in renal failure model using PK-Sim and Simcyp , 한국응용약물학회 추계국제학술대회 (Oct, 2021)
  17. [학술회의] 김소희, A key issues for new drug development: Drug interaction with hurbal substances , 2018 (사)한국응용약물학회 워크샵 , pp.45 (Dec, 2018)
  18. [학술회의] 곽은혜, 김소희, Pharmacokinetic changes of tofacitinib in rat model of diabetes mellitus induced by streptozotocin , 제70차 대한약리학회 추계학술대회 (Nov, 2018)
  19. [학술회의] 박성욱, 김소희, Pharmacokinetics drug interaction of tofacitinib in rats: Effects of grape fruit juice and St. John's wort. , 제70차 대한약리학회 추계학술대회 (Nov, 2018)
  20. [학술회의] 김소희, 김지은, 박문영, EFFECT OF CYTOCHROME P450 (CYP) INDUCERS AND INHIBITORS ON THE PHARMACOKINETICS OF TOFACITINIB IN RAT , 제 69차 대한약리학회 추계학술대회 (Nov, 2017)
  21. [학술회의] 김소희, 박주호, AZOLE ANTIFUNGAL DRUGS PROMOTES AUTOPHAGY THROUGH LKB1-AMPK PATHWAY IN HUMAN BREAST CANCER , 제 69차 대한약리학회 추계학술대회 (Nov, 2017)
  22. [학술회의] 김소희, 이지상, PHARMACOKINETICS OF TOFACITINIB IN RAT : RELEVANCE OF FIRS-PASS EFFECT FROM HEPATIC AND INTESTINAL UPTAKE , 제 69차 대한약리학회 추계학술대회 (Nov, 2017)
  23. [학술회의] 김소희, 박주호, Azole antifungal drugs induced apoptosis and autophagy by AMPK pathway in human breast cancer , 2017 Annual Meeting of The Korean Society of Applied Pharmacology (Oct, 2017)
  24. [학술회의] 김소희, 이지상, Dose-dependent pharmacokinetics of tofacitinib in rats : Hepatic and gastrointestinal first-pass effect , 2017 Annual Meeting of The Korean Society of Applied Pharmacology (Oct, 2017)
  25. [학술회의] 김소희, 방은숙, 이재명, 이주원, 정태석, Low Level of Meropenem Concentration in Brain Dead Organ Donors:A Single Center Parmacokinetic Study , 제 25회 기초의학 학술대회 (Jun, 2017)
  26. [학술회의] 이지상, 김소희, 정윤석, 최용준, Yilan Jin, 옥소영, Inverse correlation between trabecular bone score and urinary pentosidine levels in patients with type 2 diabetes , 2016 Annual Meeting of the Korean Society of Applied Pharmacology (Oct, 2016)
  27. [학술회의] 김지은, 김소희, 박문영, 박주호, 이지상, Simple determination of tofacitinib, a JAK inhibitor, in plasma, urine and tissue homogenates by high-performance liquid chromatography , 2016 Annual Meeting of the Korean Society of Applied Pharmacology (Oct, 2016)
  28. [학술회의] 강향리, 김소희, 김선재, 임수정, Increased chemoresistance by butyrate in human colon cancer cells , 2015 추계 응용약물학회 학술대회 (Oct, 2015)
  29. [학술회의] 배성훈, 김소희, 박유진, 김혜숙, 최현겸, Effects of azole antifungal drugs in the human breast cancer as cancer therapeutic agents , 2015 추계 응용약물학회 학술대회 (Oct, 2015)
  30. [학술회의] 김소희, CYP24A1 in Lung Adenocarcinoma: Alterations in Metabolism of Vitamin D , 2013 Annual Meeting of The Korean Society of Applied Pharmacology , pp.79 -85 (Oct, 2013)
저서 및 번역
  1. [저서] 정이숙, 김소희, 장선영, 진효언, 생체장벽의 이해와 제어 기술 (Dec, 2022)
  2. [저서] 이석용, 김소희, 강건욱, 김민선, 명창선, 박필훈, 배수경, 배정우, 손의동, 신상미, 이용수, 이윤정, 이정미, 장춘곤, 정재훈, 정철호, 정혜진, 제현동, 조정숙, 최영희, 최현진, 약물작용기본이론 (Jun, 2015)
  3. [저서] 김소희, 감경만, 강건욱, 곽미경, 김민선, 김상건, 김영미, 김용기, 김윤균, 김현정, 김형춘, 김화정, 노민수, 명창선, 박규환, 박성규, 박필훈, 배수경, 배정우, 손기호, 손의동, 송경, 송윤선, 신상미, 신은주, 안상미, 오기완, 옥민호, 은재순, 이석용, 이용수, 이진우, 임동순, 임형신, 장춘곤, 정재훈, 정철호, 정혜진, 제현동, 조정숙, 최동영, 최영희, 최지웅, 최창익, 최현진, 하헌주, 한선영, 허주영, 홍진태, 약물학 (Mar, 2015)
특허 및 기타
  1. [특허] 김소희, 김형수, 최현겸, 이소사쿠라네틴을 포함하는 당뇨병 예방, 개선 또는 치료용 조성물 (출원) (10-2024-0149558) (Oct, 2024)
  2. [특허] 김소희, 김형수, 배성훈, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 간경화의 예방 또는 치료용 약학적 조성물 (출원) (202280070655.9) (R0420CN) (Apr, 2024)
  3. [특허] 김소희, 김형수, 배성훈, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 간경화의 예방 또는 치료용 약학적 조성물 (출원) (18/698,383) (R0420US) (Apr, 2024)
  4. [특허] 김소희, 최현겸, 약물 담지 리포좀의 약물 방출 촉진용 조성물 (출원) (18/122,284) (R0420US) (Mar, 2023)
  5. [특허] 김소희, 최현겸, 약물 담지 리포좀의 약물 방출 촉진용 조성물 (출원) (10-2023-0020822) (Feb, 2023)
  6. [특허] 김소희, 김형수, 박예지, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 (등록) (10-2489977) (Jan, 2023)
  7. [특허] 김소희, 김형수, 배성훈, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 간경화의 예방 또는 치료용 약학적 조성물 (출원) (PCT/KR2022/016128) (Oct, 2022)
  8. [특허] 김소희, 김형수, 배성훈, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 간경화의 예방 또는 치료용 약학적 조성물 (출원) (10-2021-0141173) (Oct, 2021)
  9. [특허] 김소희, 김형수, 박예지, 이소사쿠라네틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 (출원) (PCT/KR2021/006718) (May, 2021)
  10. [특허] 곽종영, 김소희, 송민규, 최민호, 나노섬유 기반 장기간 초대 간세포 3차원 배양시스템 및 배양방법 (출원) (16/649,986) (R0420US) (Mar, 2020)
  11. [특허] 곽종영, 김소희, 송민규, 최민호, 나노섬유 기반 장기간 초대 간세포 3차원 배양시스템 및 배양방법 (등록) (10-2062465) (Dec, 2019)
  12. [특허] 곽종영, 김소희, 송민규, 최민호, 나노섬유 기반 장기간 초대 간세포 3차원 배양시스템 및 배양방법 (출원) (PCT/KR2018/011215) (Sep, 2018)
  13. [특허] 김소희, 강향리, CPT1을 유효성분으로 포함하는 뷰티레이트 내성 대장암 진단용 바이오마커 조성물 (등록) (10-1864928) (May, 2018)
갤러리